Autism Linked to Excess Neurons

Crystal Phend, via a kind Larry Winkler email:

Children with autism appear to have bigger brains with more neurons than normal for their age, a small preliminary study affirmed.
Postmortem examinations of seven boys with autism showed 67% more neurons in the prefrontal cortex (1.94 billion), which controls social and emotional development as well as communication, compared with six controls (1.16 billion, P=0.002), Eric Courchesne, PhD, of the University of California San Diego, and colleagues found.
Autistic brains also weighed 17.6% above normal for age (P=0.001), the group reported in the Nov. 9 issue of the Journal of the American Medical Association.
Point out that the brains from autistic boys in this study were 17.6% above what is considered normal brain weight based on age.
Neuron counts in the autistic children should have been accompanied by brain weights of 29.4% versus the observed 17.6% enlargement, they said. “Thus, the size of the autistic brain, overlarge though it is, might actually underestimate the pathology of excess neuron numbers,” the group explained.