Why it’s not “Rain Woman”: Women have fewer cognitive disorders than men do because their bodies are better at ignoring the mutations which cause them

The Economist:

AUTISM is a strange condition. Sometimes its symptoms of “social blindness” (an inability to read or comprehend the emotions of others) occur alone. This is dubbed high-functioning autism, or Asperger’s syndrome. Though their fellow men and women may regard them as a bit odd, high-functioning autists are often successful (sometimes very successful) members of society. On other occasions, though, autism manifests as part of a range of cognitive problems. Then, the condition is debilitating. What is common to those on all parts of the so-called autistic spectrum is that they are more often men than women—so much more often that one school of thought suggests autism is an extreme manifestation of what it means, mentally, to be male. Boys are four times more likely to be diagnosed with autism than girls are. For high-functioning autism, the ratio is seven to one.

Moreover, what is true of autism is true, to a lesser extent, of a lot of other neurological and cognitive disorders. Attention deficit hyperactivity disorder (ADHD) is diagnosed around three times more often in boys than in girls. “Intellectual disability”, a catch-all term for congenital low IQ, is 30-50% more common in boys, as is epilepsy. In fact, these disorders frequently show up in combination. For instance, children diagnosed with an autistic-spectrum disorder often also receive a diagnosis of ADHD.