The One Hundred Year Study on Artificial Intelligence, launched in the fall of 2014, is a long-term investigation of the field of Artificial Intelligence (AI) and its influences on people, their communities, and society. It considers the science, engineering, and deployment of AI-enabled computing systems. As its core activity, the Standing Committee that oversees the One Hundred Year Study forms a Study Panel every five years to assess the current state of AI. The Study Panel reviews AI’s progress in the years following the immediately prior report, envisions the potential advances that lie ahead, and describes the technical and societal challenges and opportunities these advances raise, including in such arenas as ethics, economics, and the design of systems compatible with human cognition. The overarching purpose of the One Hundred Year Study’s periodic expert review is to provide a collected and connected set of reflections about AI and its influences as the field advances. The studies are expected to develop syntheses and assessments that provide expert-informed guidance for directions in AI research, development, and systems design, as well as programs and policies to help ensure that these systems broadly benefit individuals and society.